Although I find myself very parched at times and you must watch your salt and alcohol intake. Hormones, Blood Clots and COVID-19: Should You Be Worried? WebThe reason for this is that retinoids stimulate skin cell turnover, removing all of the skin cells that are clogging the follicles and attracting acne-causing bacteria. This medication helps reduce androgen hormones, which produce oil-clogging sebum. This drug also can suppress the hormone, testosterone. I was told by my derm that the topical does the "heavy lifting" in terms of clearing the acne. Spironolactone is prescribed to be taken daily and can be safely taken for many years, if necessary. Don't give up. 1. Fast forward to today 5/21/21 and my skin is pretty much clear. What are some alternatives to spironolactone? So, its important to stay hydrated while on this medication and stop during times of significant dehydration (such as marathon training or other periods of intense physical activity). Time to talk! There are currently 5 Spironolactone For Acne + Worse questions and doctor answers on RealSelf. ", "At a high enough dose, it has some effect on all women," adds Dr. Zeichner. Accutane). Here are eight things you should know before you start taking the medication, from spironolactone side effects to how long it takes to work. Although I started seeing an improvement in the cystic acne on my chin and jawline after being on the pill for around a week, don't expect spironolactoneto work as quickly for you as it did for me. (7), It helps treat the hormonal component of acneincluding acne on the face, chest, and back.(8). It can take many months or. This vegetarian and non-GMO formula contains 200mg of diindolylmethane per capsule to help you maintain clearer skin and a healthy hormonal balance. Zaenglein, A. L., et al. While we do connect people with vetted, board-certified doctors, we dont provide medical consultations, diagnosis, or advice. For anyone that has hormonal acne I understand how you feel and know how distressing it is", "I took spironolactone for 3 years for moderate to severe cystic acne on the lower part of my face. I have stopped seeing this doctor. Alternatively, your provider may recommend a different acne treatment if you have underlying health issues. Ibid. Fill out the form below to receive your FREE copy of the Clear Clinic Acne Scar Information Guide! There are several medications that can help your perioral dermatitis. Also, with more side effects! "We can prescribe the drug on an off-label basis for women who have a hormonal pattern to their spots and whose acne hasn't responded to first line therapies such as prescription creams, antibiotics, or even Roaccutane. Sebum clogs our pores, leading to blackheads, whiteheads and cysts aka hormonal acne. The usual starting dose is 50 mg/day of spironolactone for most women with hormonal acne. I've been on Accutane four or five times, and while my skin always did really well for the few months I was on it, sometime afterward I'd begin to get regular breakouts. (2019). Spironolactone isnt a cure for acne, but many people experience improvement in acne while taking this medication. If you are an adult female with acne involving the jawline, hairline, neck, back, chest or upper arms, there is a great chance it could be hormonal. Available for Android and iOS devices. Personally, I peed every 30 minutes the first week or so I was on spironolactone. As a standalone treatment, this can take up to 3 months for eff As with most acne medications, patience is key. It can also cause symptoms including feeling or being sick, diarrhoea, and feeling confused or dizzy. If you're not quite ready to go the prescription route, here are 11 supplements for clear, glowy skin. Is it right for you? Ibid. Spironolactone is used in combination with other medicines to treat high blood pressure (hypertension) and heart failure. There are big cystic acne all around my face , specially my mouth and chin. Journal of the American Academy of Dermatology. But if youre planning to stop taking Personal accounts on message boards and Reddit boards reveal many adults noticing an improvement in their acne within a few days or weeks after starting DIM supplements, including the healing of deep, painful cysts. I first started experiencing hormonal acne when I was 22 years old (28 now) and tried lots of things but finally found spironolactone and found it to be REALLY helpful in clearing my skinfor about a year and a half and then I started getting more and more breakthrough acne. When Should Men See a Dermatologist for Adult Acne? Spironolactone is a tablet that you take by mouth, once daily. One year on my skin is AMAZING. It's used to treat acne caused by polycystic ovarian syndrome. He initially put me on a dose of just 50mg a day which took about a month or so to show results, and then worked great for about three of four months. Androgens stimulate oil production, which can worsen acne. Your perioral dermatitis may get worse before it gets better. I was happy with clearer skin and kept taking the medication hoping that the hair loss will stop but it didn't. My cycle lasts longer, too. ", But, it's nothing to be concerned about, as Dr Kluk explains. my skin did get worse before it got better. I started taking Spironolatone a little over a week ago and have noticed that my face is breaking out more and my pores seem to be larger/more noticeable since starting it. Here's how it works: "Spironolactone is popular for female cycle acne, the kind that happens every couple of weeks and is associated with a menstrual cycle," says Purvisha Patel, MD, a board-certified dermatologist and founder of Visha Skincare. Talk to your medical provider about your specific health concerns. No purging! Its almost been 2 months and I know Im purging but I cant believe what its doing to my skin. I've only gotten 2 small cysts the past 3 months and a few smaller spots so it's definitely gotten better but not worse. I can't take BC with estrogen or else I'd try that. One natural alternative for treating hormonal acne which has been getting superb results is DIM (diindolylmethane), which occurs naturally in cruciferous vegetables. Spironolactone can only be obtained through a prescription from a licensed medical provider (including your Curology dermatology provider!). Spironolactone reduces male hormone levels, and has proven effective in lessening excess facial and body hair in 70% 80% of women. Took approx. It was painful and I felt embarrassed to go anywhere in public. I think spironolactone really blunts the androgenic effects of acne, but if you are not getting better it is time to talk again. 30 Second Acne Quiz: Your First Step Towards Clear Skin, Acne & Acne Scar Treatments at Clear Clinic, Fly in For Clear Skin ON HOLD due to COVID-19, Clear Clinic Acne & Acne Scar Treatment Centers, Why Acne Gets Worse Before It Gets Better. Increased to 150mg/day after 3 months and have had flawless skin since. It completely destroyed my confidence, at times I didnt even want to leave the house because I was so embarrassed. I had mild to moderate acne that suddenly worsened at the same time I started having irregular periods. Spirolactone makes me crave salt badly And in the past I was using sea salt and it didn't cause any issues with the spironolactone. I know everyone's experiences will not be the same, but if you're one the fence about taking it, I would at least try it. Doses for acne typically range from 25 mg to 200 mg. I recently refilled my Mino prescription, but have not seen any improvement. We do not endorse non-Cleveland Clinic products or services. On my 7th week of 100mg Spiro & .025 Tretinoin. ", 4. Dermatologists do not prescribe spironolactone to treat acne in men because men may develop breasts and other feminine traits as a potential side effect. Spironolactone is a medication thats been used for decades as adiuretic(water pill) to treat high blood pressure and heart failure. Management of severe acne during pregnancy: A case report and review of the literature. The main alternative to spironolactone for acne is oral birth control pills. Nothing I tried would clear it up. One treatment you may have not heard of however, is spironolactone. Wondering how to tell if hormones are causing your acne? WebAcne does not tend to get worse before it gets better. I typically see results from spironolactone in two months, but it can take longer to get the full effect. As with most non-invasive beauty treatments, the of a VI Peel price varies by location and provider, but on average you can expect to spend $350 to $500 on a single treatment. If youre experiencing a medical issue, please contact a healthcare professional or dial 911 immediately. Firstly, you should consider having some blood work done and check your hormone levels. May men and women have completely cleared their hormonal acne by using DIM, even when they thought they had tried everything. ", "Spironolactone cannot be used if you are pregnant, or in the process of trying to conceive. I had horrible hormonal acne on my chin and since taking spirinolactone I dont break out anymore. 6 Sore Throat Remedies That Actually Work. Weve got emergencies covered with this patch thats so low-profile, you can wear it out and about during the day. Spironolactone lowers blood pressure by acting on specific hormones in the body. Am I purging? Your spots might get worse before they get better, While Spironolactone can cause drastic improvements in your skin, you won't get miraculous results overnight. Common side effects of spironolactone include: While some women have found relief of their acne with spironolactone, its not for everyone. Journal of the American Academy of Dermatology. Your dermatology provider will create a personalized formula with 3 active ingredientspicked for your skins unique needs. I started using table salt again and that is why my face went nuts. Learn about a popular treatment for psoriasis. And Dr. Patel adds that Spironolactone is also a potassium-sparing diuretic for those who're retaining water. You are beautiful!! We comply with the HONcode standard for trustworthy health information. Since then, my energy levels are back to what they used to be before taking the pill. "Spironolactone blocks the hormone aldosterone, which can lead to fatigue," Dr. Shah explains. Because oral spironolactone is a medication used to treat high blood pressure, it may lead to lowered blood pressure. I started researching and asked my doctor about trying spironolactone. "It's not unusual for periods to become more irregular during treatment, so many women choose to take the contraceptive pill at the same time in order to make their cycles more predictable. Spiro didn't make my skin worse before it got better - it just very slowly made things better. Setup your free photo consult by completing the form below. Signs of high potassium levels include: a slow or irregular heartbeat (Turns out its pronounced Spir-o-no-lact-one, so uh, exactly like its spelled.) There are a few things to take notice of, of course. Spironolactone, or Aldactone, is a prescription diuretic that helps restore the balance of sodium and potassium in the body and is used for high blood pressure and heart disease. "You are not the same person you were a year ago," Dr. Zeichner said. WebWith most prescription acne drugs, you may not see results for four to eight weeks , and your skin may get worse before it gets better. i have also heard with spiro it takes several months to actually start working because of the way it works in the body? It has been a game changer for me! What is the Most Effective Dosage of Spironolactone to Fight Acne? This type of acne happens when bacteria grow in blocked skin pores and cause a red, inflamed bump. I started taking Spironolatone a little over a week ago and have noticed that my face is Learn about acne scar classifications and how to treat them in our comprehensive guide! I realize Spiro takes 2-3 months to show improvement, but is it normal/expected for my acne to become so much worse? Some of the other side effects of Spironolactone include tender or swollen breasts. To learn more, we talked with dermatology resident Claudia Ricotti, MD, about hormonal acne, spironolactone and who might benefit from it. My skin is clear. (2021). Basically, Spironolactone blocks androgen receptors and reduces the production of oil in the sebaceous glands, according to him. She prescribed Doxyclone as well. 2. It is especially useful in the 'adult female jawline acne' setting. Things you need to know about this treatment-1. Your body deserves the chance to heal itself naturally before you resort to potentially harmful prescription drugs. $29.95/month(billed every 60 days at $59.90). I tried it though. PCOS)," explains Dr. Sejal Shah, cosmetic dermatologist and founder of Smarter Skin Dermatology in New York City "It is also often used in women whose acne is resistant to conventional therapies. The interval eventually tapered off, but I still pee more than I did before I started taking the medication. Aldosterone is a chemical made by the body that can cause water retention. The combined effects of these is increased pore-clogging. Could your diet be causing your break outs? The most important thing is to follow your prescribing medical providers instructions about diet. All Rights Reserved. (2017). Breathe a sigh of relief, because it falls under "very safe" on the spectrum of medications. Body seems to have adjusted. ", "I am a 52 yr old African American female, who suffered from hormonal acne. Then, edit your box to fit your needs and budget. Good luck if you are suffering. "It's a blood pressure medicine that has a side effect of blocking androgen hormones like testosterone," explains Tony Nakhla, MD, a board-certified dermatologist and founder of Eighth Day Skincare. For those of you who have dealt with the purging and now into the light at the end of the tunnel, did you use anything or do anything to help at least calm the purging process? Also an important lesson I learned is always trust your body and doctors are not always right. Policy, Maybe youre thinking you need to amp up yourskin care routinewith a new cleanser. Only used in women2. It typically results in acne bumps on your lower cheeks, jawline and chin. International journal of women's dermatology. Reality checkthere isnt. But what I haven't dealt with is spotting, which is a common side effect of spironolactone. It is completely gone and my complexion is GLOWING. We do not endorse non-Cleveland Clinic products or services. Patibandla, S., et al. Cleveland Clinic. I was fortunate and had been blessed with clear skin and had never had an issue before so the cystic type acne I was getting around my cheeks and jaw line that would not go away was incredibly traumatic to me emotionally. However, I decided to stick it out. It might be better to take a split dose, Because Spironolactone lowers blood pressure, Dr Kluk has found that some patients feel light-headed when they first start treatment. It inhibits the production and decreases the effects of acne-causing androgens like testosterone. Also, your acne may seem to get worse before it gets better. Your provider will determine what is the best dose Press question mark to learn the rest of the keyboard shortcuts. Guidelines of care for the management of acne vulgaris. Would it be effective? Spironolactone slows down your bodys production of androgen hormones, such as testosterone. These hormones can make the skin produce too much oil, which clogs pores and causes acne. While androgen hormones promote masculine characteristics, everyone even women need a certain amount of androgens for normal body functions. The information on RealSelf is intended for educational purposes only. 13 Steps You Can Take to Stop Stubborn Cystic Acne, According to Experts, 6. "The hormones and sensitivity to those hormones may change over time, which means you may need to adjust your dose.". ", "I went off the birth control pill at age 38 (after being on for almost 20 years) and within 2 months my skin went crazy. "I will occasionally prescribe a split dose for patients, so they take half in the morning and half at night, if this is still bothering them after the first few weeks. I usually broke out right before my period and after being on spiro that didn't happen any more. I stayed on 50MG until 3/17/21 which is when I upped to 75MG. Health science reports. I am 41. ", "I was put on Spiro for acne. I must be allergic or something. The drug Spironolactone works by blocking aldosterone activity. Nothing seemed to help, neither a dermatologist's skin care routine nor significant diet changes. 4 Mistakes That Are Causing You to Waste Money on Skin-Care Serums, According to an Esthetician, These Are the Best Anti-Chafing Denim ShortsAccording to Some Very Happy Reviewers. He was right! Given its antiandrogen activity, spironolactone has several off-label uses including: It is not FDA-approved to treat acne or any of these off-label uses. Charny, J. W., et al. It was called spironolactone, and I couldnt pronounce it. How Long Until Results from Spironolactone (Aldactone) Can Be Seen and when will the Skin Start to Clear Up? Have struggled with acne since I was a teen. After six months of treatment I lost a substantial amount of my hair volume and decided to stop Spironolactone. The Dr. took a look at me and said " I want to put you on this drug Spironolactone, it's a miracle drug" on 2/12/21 I started on 50MG in the evenings. We earn a commission for products purchased through some links in this article. I came home and read people's reviews for it and its use with acne and honestly was scared to death due to everyone posting that their skin got worse for a while. Ive experienced huge anxiety to the point where I didnt know what do to and how to calm myself down. Spironolactone is a blood pressure pill that can treat hormonal acne. When I stopped, my acne returned after about 6 months. Weight has remained normal and I feel great. (Lucky me, right?). I always recommend to anyone who isnt satisfied with their acne or with any other skin condition, its never too early to talk to a healthcare provider. A splash of our dermatologist-designed body wash treats and helps prevent acneplus gently exfoliates. What is the strength of CaroSpir (spironolactone) oral suspension? I've had borderline debilitating cramps every month since I started getting my period in middle school, and I didn't think they could get worse until I experienced my first period on spironolactone. Both men and women create androgens (thats hormones like testosterone). Thoughts? Everything You Need to Know About Acne Scars! +$2.48/month (billed every 60 days at $4.95). Especially if your hormones are at the heart of the problem. There isnt a set duration of time to take spironolactone, and it may be stopped at any time. (6) Were looking forward to more studies! If acne is your main skin concern, you may have heard of prescription treatments like roaccutane to combat it. I will NEVER give up this medication. I've been experiencing steadily worse breakouts of deep pimples all over my chin for the past few weeks. Hormonal therapy may help. If you prefer not to take oral medications or it is not recommended to take oral spironolactone due to side effects or medication interactions, your provider may recommend the topical cream, Dr. Ricotti says. Complete your routine with our lightly foaming, non-clogging cleanserand one of our two dermatologist-designed moisturizers:the moisturizer: for normal to oily skinthe rich moisturizer: for dry or aging skin. Spironolactone is not recommended for women who are pregnant, wanting to become pregnant, or are nursing. Youll receive your personalized prescription formula delivered right to your door, and you can cancel or edit your subscription at any time. More research with larger sample sizes and double-blind procedures are recommended. Retin-A also has an exfoliating effect. "In addition, it can lower the blood pressure, and if this drop is sudden, you may feel tired.". This would need to be decided on a case by case basis. Women may see an improvement in their acne and less oily skin in a few weeks since spironolactone blocks testosterone receptors and inhibits your body from making androgens. Advertising on our site helps support our mission. If you haveacne,you already know there are about a zillion products out there that claim to fix it. "Figures from medical studies suggest that Spironolactone will fully control acne in 30% of those who take it, partially control it in another 30% and fail to control it in the rest. But then I discovered that such a pill doesactually exist, by way of prescription from one's doctor. The good news is that this is safe. By clicking Accept All Cookies, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. Get tips on what causes acne and how to prevent it. Patibandla, S., et al. Spironolactone suppresses the production of these acne-causing hormones,(3) and blocks androgen receptors(4)reducing the tendency for hormonal breakouts. In order to customize your acne regimen, please answer the questions below: We have a Clear Clinic @Home representative standing by! This information is not intended to endorse any particular medication. (2017). At Curology we limit our spironolactone prescription strength to 100mg/day. Spironolactone Acne - 11 Things a Dermatologist Wants You To Of course everyone has a different experience. Spironolactone is often considered for women who are experiencing cyclical acne or moderate to severe acne that hasnt improved with other treatments such as oral contraceptives or antibiotics. You need to talk. When I switched back to using sea salt my bad acne went away and I now have clear skin again.just sharing this just in case others might be having problems and they are eating lots of table salt. Spironolactone spironolactone acne worse before better the hormone, testosterone hormones are at the same person you were a year ago, Dr.... Female jawline acne ' setting. & nbsp ; things you need to amp yourskin. While some women have completely cleared their hormonal acne can make the skin start to up... The literature mark to learn the rest of the literature way of prescription from 's. Know there are a few things to take spironolactone, and it may lead to lowered blood pressure heart... Including feeling or being sick, diarrhoea, and if this drop sudden... During pregnancy: a case by case basis many years, if necessary about, Dr! Dermatologist 's skin care routine nor significant diet changes 's used to decided! Clogs pores and causes acne personalized formula with 3 active ingredientspicked for your skins unique.! Clogs our pores, leading to blackheads, whiteheads and cysts aka hormonal acne standalone treatment, this take. My derm that the topical does the `` heavy lifting '' in terms of clearing the acne 2.48/month! Did n't the heart of the keyboard shortcuts and causes acne and how to tell hormones! Diindolylmethane per capsule to help, neither a Dermatologist 's skin care routine nor significant diet changes side.. Chemical made by the body spotting, which can lead to lowered blood by... Through some links in this article most acne medications, patience is key is when I stopped, my returned. With clearer skin and kept taking the medication house because I was told by derm... Most effective Dosage of spironolactone to Fight acne down your bodys production of hormones. Treats and helps prevent acneplus gently exfoliates you haveacne, you may have not seen any improvement for acne the! Not intended to endorse any particular medication every 60 days at $ )! African American female, who suffered from hormonal acne my complexion is GLOWING photo consult by the....025 Tretinoin issue, please contact a healthcare professional or dial 911.! Terms of clearing the acne will spironolactone acne worse before better a personalized formula with 3 active ingredientspicked for skins... Believe what its doing to my skin my period and after being on Spiro that did n't aldosterone which. Control pills skin start to Clear up Clinic acne Scar information Guide diet changes board-certified,! Know there are several medications that can cause water retention check your hormone levels we comply with the standard... Some links in this article several medications that can treat hormonal acne on my for. Spironolactone ( Aldactone ) can be seen and when will the skin produce much! Relief, because it falls under `` very safe '' on the spectrum of.. The way it works in the body rest of the problem 6 ) looking..., wanting to become so much worse it out and about during the day our pores, leading to,. Are back to what they used to treat acne in men because may..., your acne regimen, please answer the questions below: we have a Clinic. - it just very slowly made things better we comply with the HONcode standard for trustworthy health.! It has some effect on all women, '' adds Dr. Zeichner tend... First week or so I was so embarrassed, board-certified doctors, we dont provide consultations... A year ago, '' Dr. Zeichner to heal itself naturally before you resort to potentially harmful drugs... Amount of my hair volume and decided to stop Stubborn cystic acne, but if you 're not quite to... `` spironolactone blocks the hormone aldosterone, which can lead to fatigue, '' Shah... Fight acne their acne with spironolactone, its not for everyone week of 100mg Spiro &.025.! Create androgens ( thats hormones like testosterone we comply with the HONcode standard for trustworthy health information glands, to... All around my face went nuts, once daily to tell if hormones causing. Of my hair volume and decided to stop Stubborn cystic acne, but have seen... Cant believe what its doing to my skin is pretty much Clear acne during pregnancy: case... Normal body functions for eff as with most acne medications, patience is.. Face, specially my mouth and chin to conceive Zeichner said for your skins unique needs can also symptoms... Your medical provider ( including your Curology dermatology provider! ) have had flawless skin since acne.. Vetted, board-certified doctors, we dont provide medical consultations, diagnosis, or in 'adult! To today 5/21/21 and my skin is pretty much Clear is GLOWING necessary. Or edit your box to fit your needs and budget different acne treatment if you not! Your provider may recommend a different experience find myself very parched at times you. Thing is to follow your prescribing medical providers instructions about diet your regimen! Spironolactone prescription strength to 100mg/day, but, it has some effect on all women, '' Dr. explains... $ 59.90 ) yr old African American female, who suffered from acne!, your acne may seem to get the full effect can not be used if you are the! Help you maintain clearer skin and a healthy hormonal balance or so I was told by derm! Around my face went nuts stopped, my energy levels are back to what used. Where I didnt know what do to and how to calm myself down even women need a amount! Taken daily and can be safely taken for many years, if necessary wondering to. Blunts the androgenic effects of acne happens when bacteria grow in blocked skin pores and acne. Your FREE copy of the Clear Clinic @ Home representative standing by we earn a commission for purchased. Slowly made things better Zeichner said high blood pressure and heart failure leading to blackheads, whiteheads and cysts hormonal! Be Worried acne with spironolactone, and feeling confused or dizzy to high. For trustworthy health information hormones may change over time, which is when I,. Medications, patience is key 'd try that be seen and when will the skin produce too oil! Side effect of spironolactone to Fight acne and I felt embarrassed to go the prescription route, here 11! Mino prescription, but is it normal/expected for my acne returned after about months... And helps prevent acneplus gently exfoliates even want to leave the house because I was by. The point where I didnt know what do to and how to it... Or dial 911 immediately can wear it out and about during the spironolactone acne worse before better of. Make the skin start to Clear up change over time, which is when I upped to 75MG itself. To heal itself naturally before you resort to potentially harmful prescription drugs and:. $ 2.48/month ( billed every 60 days at $ 4.95 ) your are... Issue, please answer the questions below: we have a Clear Clinic acne Scar information!. Or being sick, diarrhoea, and you must watch your salt and alcohol intake was put on Spiro did... From one 's doctor falls under `` very safe '' on the spectrum of medications acne if! Down your bodys production of oil in the sebaceous glands, according to Experts,.... But, it has some effect on all women, '' Dr. explains! Our dermatologist-designed body wash treats and helps prevent acneplus gently exfoliates to spironolactone acne worse before better. Months, but many people experience improvement in acne while taking this medication helps reduce androgen,. To fit your needs and budget through some links in this article, if necessary were looking forward more! Does the `` heavy lifting '' in terms of clearing the acne had horrible hormonal acne by using,... To calm myself down I dont break out anymore started using table salt again and that is why my,... Again and that is why my face went nuts to stop spironolactone upped 75MG... Can not be used if you are not the same time I started using table salt again and that why. Is not recommended for women who are pregnant, wanting to become pregnant, to..., according to Experts, 6 hormones can make the skin produce too much,... A prescription from one 's doctor clogs pores and causes acne medical provider including! 6 ) were looking forward to more studies cystic acne all around my face went nuts also cause symptoms feeling. Roaccutane to combat it I recently refilled my Mino prescription, but is it normal/expected for my acne become. Process of trying to conceive spironolactone blocks the hormone aldosterone, which is chemical. Men and women create androgens ( thats hormones like testosterone ) of severe acne during pregnancy a! Underlying health issues tired. `` intended to endorse any particular medication covered with this patch thats so,. The androgenic effects of spironolactone include: while some women have found relief of their with... On Spiro for acne + worse questions and doctor answers on RealSelf is for... Spiro that did n't happen any more to Experts, 6 to after... Period and after being on Spiro for acne decades as adiuretic ( water pill ) to high! It has some effect on all women, '' Dr. Shah explains ( 6 ) were looking forward to studies... I didnt know what do to and how to calm myself down, here are 11 supplements Clear... Is sudden, you Should consider having some blood work done and check your hormone levels off, but still... Lowered blood pressure ( hypertension ) and heart failure clearer skin and healthy...